[Kev Tshawb Fawb Txhais Lus]
Hydrogels yog tes hauj lwm ntawm hydrophilic polymer saw, hu ua colloidal gels, uas cov dej yog qhov nruab nrab tawg. Peb-dimensional software yog vim hydrophilic polymer chains tuav ua ke los ntawm kev hla kev sib txuas. Vim yog kev hla tus ntoo khaub lig-txuas, kev ua haujlwm ruaj khov ntawm cov txheej txheem hydrogel yuav tsis yaj los ntawm cov dej ntau (doi: 10.1021/acs.jchemed.6b00389). Hydrogels kuj tseem nqus tau zoo (lawv tuaj yeem muaj ntau dua 90% dej) ntuj lossis hluavtaws polymer sib txuas. Lo lus "hydrogel" thawj zaug tshwm sim hauv cov ntawv sau xyoo 1894 (doi: 10.1007/BF01830147). Thaum pib, kev tshawb fawb ntawm hydrogels tsom mus rau qhov no yooj yim sib txuas sib txuas ua ke polymer network los kawm nws cov yam ntxwv tseem ceeb, xws li o/o kinetics thiab sib npaug sib npaug, daws qhov sib kis, ntim theem hloov pauv thiab swb kev sib txhuam, thiab Tshawb nrhiav cov ntawv thov no. Xws li ophthalmology thiab xa tshuaj. Nrog kev txhim kho txuas ntxiv ntawm kev tshawb fawb hydrogel, nws lub hom phiaj tau hloov pauv los ntawm cov tes hauj lwm yooj yim mus rau "teb" cov tes hauj lwm. Hauv theem no, ntau yam hydrogels uas tuaj yeem teb rau kev hloov pauv ib puag ncig ib puag ncig xws li pH, qhov kub thiab txias, thiab hluav taws xob thiab sib nqus tau tsim. A hydrogel actuator uas teb rau hluav taws xob thiab sib nqus teb tau thov. Txawm li cas los xij, cov dej hydrogels nyob rau lub sijhawm ntawd feem ntau yog muag muag lossis txhav heev hauv tshuab, uas txwv tsis pub siv lawv cov peev txheej. Nrog rau lub xyoo txhiab tshiab, hydrogels kuj tau nkag mus rau lub sijhawm tshiab, nrog kev txhim kho kev txhim kho hauv lawv cov khoom siv dag zog. Qhov kev vam meej no tau coj mus rau ntau qhov kev tshawb fawb ntawm hydrogels. Niaj hnub no, ntau yam kev siv tshuaj lom neeg nrog cov qauv siv hluav taws xob tuaj yeem siv los ua hydrogels uas muaj zog dua li cov leeg thiab pob txha mos. Ib qho ntxiv, nws tseem ua tiav lwm txoj haujlwm, xws li kho tus kheej, ntau yam kev txhawb nqa cov lus teb, adhesion, super wettability, thiab lwm yam. Kev tsim kho tshiab ntawm hydrogel muaj zog tau nthuav dav nthuav cov peev txheej ntawm cov khoom siv no hauv ntau yam haujlwm, suav nrog cov neeg hlau muag, khoom siv dag zog cov nruab nrog cev, tshuaj tsim kho tshiab, thiab lwm yam (doi: /10.1021/acs.macromol.0c00238).
【Lub hom phiaj tseem ceeb:
1. Scaffold in tissue engineering (doi: 10.1002/advs.201801664).
2. Thaum siv los ua tus scaffold, hydrogel yuav muaj tib neeg lub hlwb los kho cov ntaub so ntswg. Lawv ua raws li 3D microenvironment ntawm cov cell (doi: 10.1039/C4RA12215).
3. Siv cov qhov dej uas muaj txheej txheem hydrogel-coated rau kab lis kev cai ntawm tes (doi: 10.1126/science.1116995).
4. Ib puag ncig muaj kev nyab xeeb hydrogels (tseem hu ua "ntse gels" lossis "ntse gels"). Cov hydrogels no muaj peev xwm paub txog kev hloov pauv hauv pH, qhov kub lossis qhov sib xyaw metabolite thiab tso tawm cov kev hloov pauv no (doi: 10.1016/j.jconrel.2015.09.011).
5. Txhaj tshuaj hydrogel, uas tuaj yeem siv ua cov tshuaj tua kab mob rau kev kho mob lossis kab mob cell rau kev rov tsim kho lub cev lossis cov ntaub so ntswg engineering (doi: 10.1021/acs.biomac.9b00769).
6. Kev tso tawm cov tshuaj yeeb dej caw ruaj khov. Lub zog ionic, pH thiab qhov kub tuaj yeem siv ua lub hauv paus los tswj kev tso tshuaj (doi: 10.1016/j.cocis.2010.05.016).
7. Muab kev nqus ntawm cov nqaij necrotic thiab fibrotic, degreasing thiab debridement
8. Hydrogels uas ua rau lub cev tshwj xeeb (xws li piam thaj lossis antigens) tuaj yeem siv ua biosensors lossis DDS (doi: 10.1021/cr500116a).
9. Cov ntaub pawm uas siv tas pov tseg tuaj yeem nqus zis lossis tso rau hauv daim ntaub huv (doi: 10.1016/j.eurpolymj.2014.11.024).
10. Cov iav lo ntsiab muag (silicone hydrogel, polyacrylamide, silicon-containing hydrogel).
11. EEG thiab ECG kev kho mob electrodes siv hydrogels muaj cov ntoo sib txuas sib txuas ua ke (polyethylene oxide, polyAMPS thiab polyvinylpyrrolidone).
12. Hydrogel tawg.
13. Rectal administration thiab kuaj mob.
14. Ntim ntawm quantum dots.
15. Hloov lub mis (txhim kho lub mis).
16. Kua nplaum.
17. Cov khoom siv los tswj cov av noo hauv thaj chaw qhuav.
18. Hnav khaub ncaws los kho qhov kub hnyiab lossis lwm yam tawv tawv-rau-kho qhov txhab. Qhov txhab gel yog qhov muaj txiaj ntsig zoo hauv kev tsim lossis tswj hwm qhov chaw noo.
19. Tshuaj cia rau siv sab nraud; tshwj xeeb tshaj yog cov tshuaj ionic xa los ntawm iontophoresis.
20. Cov khoom siv uas ua piv txwv cov ntaub so ntswg mucosal tsiaj, siv los ntsuas cov mucosal adhesion zog ntawm kev siv tshuaj yeeb tshuaj (doi: 10.1039/C5CC02428E).
21. Kev tsim hluav taws xob cua sov. Thaum ua ke nrog cov ions, nws tuaj yeem tshem tawm cov cua sov los ntawm cov khoom siv hluav taws xob thiab roj teeb, thiab hloov pauv cov cua sov mus rau hluav taws xob.
【Peb kev nce qib tam sim no
Tam sim no, peb daim ntawv thov hydrogel feem ntau yog siv hauv tshuaj pleev ib ce thiab kho mob, thiab tswj hwm txoj haujlwm tseem ceeb hauv kev lag luam hydrogel hauv tsev thiab txawv teb chaws raws li thev naus laus zis, thiab QA \ QC nyob ruaj khov.
Sijhawm Tshaj Tawm: Aug-11-2021